GLP 1 agonist medications

Written By Ivy Weight Loss

Ozempic. Wegovy. Mounjaro. Semaglutide. Liraglutide. 

GLP-1 agonists, also known as glucagon-like peptide-1 receptor agonists, are a class of medications used treat type 2 diabetes and obesity. They work by mimicking the action of the naturally occurring hormone GLP-1. GLP-1 agonists have several beneficial effects on glucose metabolism:

1.    Increased Insulin secretion: GLP-1 agonists enhance insulin secretion which helps to lower blood glucose levels after meals.

2.    Slowing of Gastric Emptying: These medications slow down the rate at which the stomach empties which allows you to feel full for longer.

3.    Increased Satiety: GLP-1 agonists act on your brain to reduce cravings and your overall appetite.

4.    Cardiovascular Benefits: GLP-1 agonists (semaglutide) have recently been found to significantly reduce major adverse cardiovascular events (MACE) which includes heart attacks and strokes.

Examples of GLP-1 agonists include:

  • Liraglutide (Saxenda)

  • Semaglutide (Ozempic – approved for diabetes)

  • Semaglutide (Wegovy – approved for obesity)

  • Tirzepatide (Mounjaro – approved for diabetes) *

    • works on GIP receptor as well

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